The seven-bay cast-iron upper story of 110 S. Main Street has motifs similar to those on the H. L. Jackson Building (NW8) and that were on the recently demolished 103 S. Main Street building, which bore the mark of Mesker Brothers of St. Louis. All three buildings include fleur-de-lis (characteristic of the Meskers), medallions, beading, and colonettes with arabesques and dolphins set on double-stacked floral squares. The large building (c. 1900) at 115 S. Main bears the foundry mark of George L. Mesker of Evansville, Indiana, on its facade. Its florid decoration includes urns with flowers, swags, fleur-de-lis, and colonettes. At the end of the block (126 S. Main), the substantial Beaux-Arts Classical Citizens Bank (1920) has paired columns marking the corners of the building and supporting a heavy entablature beneath a balustrade framed by laurel wreaths.
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