Some time before the Civil War, Charles Dreisbach, descendant of a German settler, constructed the Great Western Hotel on the Lewisburg-Youngmanstown turnpike (PA 45). A village sprang up around this hostelry, and in 1865 Joseph S. Raudenbush opened a general store here. When he became postmaster, Raudenbush suggested naming the village in honor of the Union army's capture of Vicksburg, Mississippi, in 1863. Vicksburg has retained its Victorian appearance.
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